Granulomatous inflammation is a form of chronic inflammation characterised by the presence of activated macrophages and T lymphocytes. In some cases, necrosis is also an issue.
Macrophages, the dominant cells in chronic inflammatory reactions, can be beneficial when the body is using them correctly. Unfortunately, the main function of a macrophage is to eliminate issues by containing the agent within a granuloma. Granulomas can induce lymphangiogenesis, which could contribute to sarcoidosis and tuberculosis disease outcomes.
Chronic Granulomatous inflammation can lead to common fungal and bacterial infections, including infections in the lungs. These infections cause skin irritation, swelling, gastrointestinal problems, swollen lymph glands, and fever, among other symptoms.
Treating Granulomatous inflammation Issues
If the symptoms of Chronic Granulomatous inflammation Disease are present, doctors will often conduct genetic testing to determine the presence of a specific genetic mutation resulting in CGD. Neutrophil function tests should also be issued to determine the functionality of neutrophil in the immune system. Treatment for Granulomatous inflammation will focus mostly on infection management and addressing symptoms as they arise.
Treatment can include exposure to constant antibiotic therapy, to protect against bacterial infections and fungal infections. Unfortunately, this over-exposure to antibiotics can negatively affect gut microbiota and also strengthen a patient’s chances of treatment-resistant infections in future.
While each patient will require a specific treatment strategy to address Granulomatous inflammation, medicinal mushrooms are arising as a potentially effective solution to both inflammation and the lymphatic swelling caused by this condition.
Medicinal Mushrooms in Granulomatous inflammation
Medicinal mushroom extracts are proven to be effective in reducing inflammatory and allergic response in the human body through immunomodulation. As bioactive adaptogens, medicinal mushrooms are capable of adapting to suit the needs of the human body, improving the performance of the immune system, and reducing potentially elevated responses to antagonizing elements.
Reishi mushroom  (Ganoderma lucidum), best known for its antioxidant, anti-inflammatory, and anti-tumour benefits, contains valuable triterpenoids and phytochemical compounds to support the proper functioning of the human body. Triterpenoids, combined with beta-glucan polysaccharides in the human body, make Reishi, one of the most powerful medicinal mushrooms around.
Triterpenoids include lucidic acid, ganoderic acid, and ganoderol. These terpenes are capable of inhibiting the release of proinflammatory substances., The phytochemical compounds can mediate the inhibition of signalling pathways for inflammation in the body. What’s more, Reishi also has antiproliferative effects, reducing the risk of damaged cells, and Reishi is cytoprotective- making it excellent for preventing hepatotoxicity.
The Polyporus Umbellatus mushroom, is also a powerful tool for the treatment of Granulomatous inflammation. This diuretic mushroom is best known for improving urinary flow and reducing the risk of UTI issues. However, it can also be extremely beneficial for other forms of physical ailment.
Polyporus mushrooms are rich in beta-glucans, capable of modulating the immune system and preventing infection. This mushroom is rich in Proteoglycans, which help with the performance of connective tissue in the body, and Triterpenes, which support many major human body functions. Probably and most significantly for Granulomatous inflammation, the Polyporus mushroom can support drainage of the lymphatic system.
Granulomatous inflammation and the Lymphatic System
Granulomatous inflammation is frequently connected to the lymphatic system. Lymphatic tracks and granulomas may affect each other, according to research. Addressing the issue of Granulomatous inflammation requires a focus not just on reducing inflammation, but on lymphatic drainage too. Blockages occurring in the lymph system overburden the organism with waste products, producing a greater burden for the immune system.
Polyporus mushrooms are effective at helping to drain the toxins from the human body with the lymph system. Throughout treatment of the inflammatory condition, it’s important to use a holistic therapy treatment like Polyporus mushroom extract to assist with transporting toxins out of the body. The ability of the Polyporus to drain the body as a diuretic and support the proper functioning of the lymphatic system is extremely useful for people with Granulomatous inflammation.
Using a combination of Polyporus and Reishi mushroom extracts in a combined treatment will offer a holistic solution for lymphatic system support, inflammation management, and general wellbeing in people with concerns regarding Granulomatous inflammation. Because these natural treatments are well tolerated, risk of additional side effects is highly unlikely.
In many cases, extracts of Polyporus and Reishi medicinal mushrooms can also be used alongside other treatment plans for Granulomatous Inflammation to drive positive recovery.